The Mouse CD71 Monoclonal Antibody (PerCP-Cyanine5.5) - R17-217-1-3/ TIB-219 (AGEL1194) is a highly specific antibody designed for research involving CD71, also known as transferrin receptor protein 1. CD71 is a cell surface protein involved in iron metabolism and is commonly overexpressed in rapidly dividing cells, making it a valuable marker for cell proliferation studies, particularly in cancer research.This monoclonal antibody, conjugated with PerCP-Cyanine5.5, offers high sensitivity and specificity for recognizing CD71 in mouse samples. It is suitable for flow cytometry applications, enabling precise detection and analysis of CD71 expression in various cell populations.
With its reliable performance and consistent results, this antibody is an essential tool for researchers studying cell proliferation, iron metabolism, and related processes.The Mouse CD71 Monoclonal Antibody (PerCP-Cyanine5.5) - R17-217-1-3/ TIB-219 (AGEL1194) is a valuable resource for investigating the role of CD71 in physiological and pathological conditions, including cancer, anemia, and cellular growth disorders. By facilitating the identification and quantification of CD71-expressing cells, this antibody contributes to a better understanding of cell biology and disease mechanisms, paving the way for potential therapeutic advancements.
Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q62351
Gene ID:
22042
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.