The Mouse CD71 Monoclonal Antibody (PE-Cyanine7 Conjugated) R17-217.1.3 (TIB-219) (AGEL1192) offered by AssayGenie is a specialized tool for researchers exploring CD71 expression and function in mouse models. This antibody, conjugated with PE-Cyanine7, provides a potent and specific means of detecting CD71, a transmembrane protein crucial for cellular iron uptake and regulation.CD71, also known as transferrin receptor protein 1, is essential for iron metabolism and homeostasis, playing a pivotal role in processes such as cell proliferation and erythropoiesis. The Mouse CD71 Monoclonal Antibody enables precise visualization and quantification of CD71 expression in various cell types, facilitating detailed investigations into iron metabolism, cell growth, and related pathways in experimental settings.
With its high specificity and sensitivity, this antibody is a valuable tool for researchers studying iron biology, hematopoiesis, and cellular proliferation in mouse models. Its compatibility with flow cytometry, immunofluorescence, and other techniques makes it versatile for diverse research applications. By enabling precise detection of CD71, this antibody contributes to a deeper understanding of iron-related disorders, cancer biology, and potential therapeutic targets involving CD71-expressing cells.Unlock the potential of your research endeavors with the Mouse CD71 Monoclonal Antibody (PE-Cyanine7 Conjugated) R17-217.1.3 (TIB-219) (AGEL1192) from AssayGenie, and delve into the intricate mechanisms governed by CD71 in mouse systems.
Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 7
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q62351
Gene ID:
22042
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.