PE/Cyanine5 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL1199)

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SKU:
AGEL1199
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
R17 217.1.3/TIB-219
Conjugation:
PE/Cy5
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The Mouse CD71 Monoclonal Antibody (PE/Cyanine5 Conjugated, R17-217.1.3, TIB-219) is a powerful tool for researchers studying CD71, a cell surface protein involved in iron metabolism and cellular proliferation. This antibody, derived from hybridoma technology, offers strong binding affinity and specificity for mouse samples. It is validated for flow cytometry applications, enabling precise detection and analysis of CD71 expression in various cell populations.CD71, also known as transferrin receptor protein 1, plays a crucial role in facilitating iron uptake by cells, making it essential for processes like erythropoiesis and cell growth. Dysregulation of CD71 expression has been implicated in various diseases, including cancer and anemia, highlighting its importance as a therapeutic target.

By understanding the function and regulation of CD71, researchers can gain insights into iron metabolism and investigate its role in disease development.The Mouse CD71 Monoclonal Antibody is a valuable tool for investigating the physiological roles of CD71 in cellular processes and disease pathogenesis. Its reliable performance and specificity make it ideal for studies in fields such as oncology, hematology, and cellular biology, providing essential insights into the intricate mechanisms associated with CD71 function.

Product Title:PE/Cyanine5 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL1199
Size:25µg, 100µg
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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