PE/Cyanine5 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL1191)

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SKU:
AGEL1191
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
R17 217.1.3/TIB-219
Conjugation:
PE/Cy5
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The Mouse CD71 Monoclonal Antibody (PE/Cyanine5 Conjugated, R17-217.1.3/TIB-219, AGEL1191) is a powerful tool for researchers studying CD71, a key protein involved in iron metabolism and cell proliferation. This antibody, specifically designed for use in flow cytometry, recognizes the CD71 protein in mouse samples with high specificity and sensitivity.CD71, also known as transferrin receptor 1, plays a crucial role in cellular iron uptake and is often upregulated in rapidly dividing cells, including cancer cells. By targeting CD71 with this monoclonal antibody, researchers can analyze and quantify the expression of this protein in a variety of cell types, shedding light on its involvement in processes such as cell growth, differentiation, and iron homeostasis.The PE/Cyanine5 conjugation of this antibody allows for multiparameter flow cytometry analysis, facilitating the simultaneous detection of CD71 along with other cell surface markers.

This feature makes the antibody especially valuable for studies investigating cell proliferation, differentiation, and iron metabolism in mouse models.Overall, the Mouse CD71 Monoclonal Antibody (PE/Cyanine5 Conjugated) provides a reliable and specific tool for researchers exploring the role of CD71 in various biological processes, including cancer development, erythropoiesis, and iron homeostasis. Its use in flow cytometry experiments ensures accurate and detailed analysis of CD71 expression in mouse samples, contributing to a better understanding of cellular dynamics and disease mechanisms.

Product Title:PE/Cyanine5 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL1191
Size:50 Tests, 100 Tests, 200 Tests
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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