The Mouse CD71 Monoclonal Antibody (PE/Cyanine5.5 Conjugated) - R17-217-1-3 (TIB-219) is a highly specific antibody designed for research applications involving CD71, also known as transferrin receptor protein 1. This antibody, derived from mouse monoclonal origin, is conjugated with PE/Cyanine5.5 for easy detection in flow cytometry and immunofluorescence studies.CD71 is a crucial cell surface receptor involved in iron uptake and metabolism, making it essential for cell proliferation and growth. The Mouse CD71 Monoclonal Antibody allows for precise detection and analysis of CD71 expression in various cell types, making it particularly useful in studies related to cell biology, cancer research, and iron metabolism.
The high specificity and sensitivity of this antibody make it an invaluable tool for researchers looking to investigate the role of CD71 in physiological and pathological processes. By enabling the precise detection of CD71 expression, this antibody facilitates a deeper understanding of cellular functions related to iron homeostasis and proliferation, opening up new avenues for research in biomedicine and therapeutics.
Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q62351
Gene ID:
22042
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.