PE Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL1189)

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SKU:
AGEL1189
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
R17 217.1.3/TIB-219
Conjugation:
PE
Frequently bought together:

Description

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PE Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The Mouse CD71 Monoclonal Antibody PE-Conjugated (R17-217.1-3 Tib-219) is a high-quality antibody designed for research involving CD71, a cell surface receptor crucial for iron metabolism and cell proliferation. This antibody, raised in mice, is specifically conjugated with PE for easy detection in flow cytometry experiments. It binds to the CD71 protein, allowing for precise detection and analysis in various cell types, making it an excellent tool for studies in cell biology, immunology, and oncology research.CD71, also known as transferrin receptor protein 1, plays a vital role in the uptake of iron-bound transferrin, facilitating iron delivery into cells for processes like DNA synthesis and cell growth.

The expression of CD71 is often upregulated in rapidly dividing cells, such as cancer cells, making it a potential target for cancer therapy and diagnostics. Understanding the function and regulation of CD71 is essential for exploring its role in various physiological and pathological conditions, including cancer, anemia, and inflammatory disorders.Overall, the Mouse CD71 Monoclonal Antibody PE-Conjugated (R17-217.1-3 Tib-219) offers researchers a reliable tool for studying CD71 expression and function, paving the way for advancements in biomedical research and potential therapeutic interventions targeting CD71-related pathways.

Product Title:PE Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL1189
Size:50 Tests, 100 Tests, 200 Tests
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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