The Mouse CD71 Monoclonal Antibody (FITC Conjugated, R17-217.1.3) is a powerful tool designed for researchers studying CD71, a cell surface receptor essential for the uptake of iron by cells. This highly specific antibody, conjugated with FITC for easy detection, is validated for use in flow cytometry applications and is optimized for detecting CD71 in mouse samples.CD71, also known as transferrin receptor protein 1, plays a vital role in iron metabolism and is crucial for cell proliferation and growth. Its overexpression is commonly observed in cancer cells, making it a target of interest in cancer research and therapy development.
By targeting CD71, researchers can gain insights into the role of iron metabolism in various cellular processes and diseases.The Mouse CD71 Monoclonal Antibody (FITC Conjugated) enables precise detection and analysis of CD71 expression in different cell types, offering valuable information for studies in oncology, cell biology, and iron metabolism. With its high sensitivity and specificity, this antibody is a key tool for investigating the functions of CD71 and its implications in disease pathology and therapeutic interventions.
Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
FITC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q62351
Gene ID:
22042
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.