The Mouse CD71 Monoclonal Antibody (FITC Conjugated, R17-217.1.3) is a specialized antibody designed for research involving the CD71 protein, also known as transferrin receptor 1. This monoclonal antibody, conjugated with FITC for fluorescence detection, is specifically tailored for studies related to CD71 expression and function in various biological samples.CD71, a cell surface protein involved in iron uptake and regulation, plays a crucial role in cell growth and proliferation. By targeting CD71, researchers can explore processes such as iron metabolism, cell cycle regulation, and potential therapeutic interventions in diseases like cancer and anemia.
The FITC conjugation of this antibody allows for precise detection and localization of CD71 in different cell types, enhancing the accuracy and efficiency of experimental analyses.With its high specificity and sensitivity, the Mouse CD71 Monoclonal Antibody (FITC Conjugated, R17-217.1.3) is a valuable tool for immunology, cell biology, and oncology research. By enabling researchers to study the dynamics of CD71 expression and its impact on cellular processes, this antibody contributes to advancing our understanding of molecular mechanisms underlying various physiological and pathological conditions.
Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
FITC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q62351
Gene ID:
22042
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.