The Mouse CD71 Monoclonal Antibody (APC-conjugated) R17-217.1.3 (TIB-219) is a powerful tool for researchers studying immune regulation and cell surface molecules in mice. This antibody, developed specifically for use in flow cytometry applications, binds to CD71, also known as the transferrin receptor protein 1, enabling accurate detection and analysis in various mouse cell types. CD71 plays a key role in iron metabolism and cellular proliferation, making it a crucial target for investigations into hematopoiesis, cancer, and other physiological processes.
With its APC conjugation, this antibody allows for robust and reliable fluorescent detection in flow cytometry experiments, offering valuable insights into CD71 expression patterns and dynamics within different cell populations.Researchers in immunology, oncology, and cell biology will find the Mouse CD71 Monoclonal Antibody (APC-conjugated) R17-217.1.3 (TIB-219) to be a valuable tool in their studies, providing precise and sensitive detection of CD71 expression in mouse tissues and cell cultures.
Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
APC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q62351
Gene ID:
22042
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.