The Mouse CD71 Monoclonal Antibody (AF647 Conjugated) - R17-217-1-3 (TIB-219) (AGEL1204) offered by AssayGenie is a cutting-edge tool for researchers working with CD71, a transmembrane glycoprotein involved in iron transport and cell proliferation. This monoclonal antibody, conjugated with AF647 for fluorescent detection, is specifically designed for use in flow cytometry and immunofluorescence applications. CD71, also known as transferrin receptor 1, plays a crucial role in the uptake of iron-containing transferrin and is highly expressed on rapidly dividing cells such as activated lymphocytes and cancer cells.
The Mouse CD71 Monoclonal Antibody provides reliable and specific binding to CD71, enabling precise identification and analysis of CD71-expressing cells in various experimental settings.Researchers studying iron metabolism, cell proliferation, and in vitro cell culture systems will find the Mouse CD71 Monoclonal Antibody (AF647 Conjugated) - R17-217-1-3 (TIB-219) (AGEL1204) to be a valuable tool for their research needs. Its high sensitivity and specificity make it an indispensable asset for investigations into cell cycle regulation, cancer biology, and iron homeostasis.
Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q62351
Gene ID:
22042
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.