The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD7 is a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell / B-cell interaction during early lymphoid development.
Product Name:
Mouse CD7 Recombinant Protein (RPES2517)
Product Code:
RPES2517
Size:
20µg
Species:
Mouse
Expressed Host:
HEK293 Cells
Synonyms:
RP23-400P17.1
Accession:
NP_033984.1
Sequence:
Met 1-Pro 150
Fusion tag:
C-His
Activity:
Measured by its ability to bind biotinylated recombinant human SECTM1 in a functional ELISA.
Endotoxin:
<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the mouse CD7 (NP_033984.1) extracellular domain (Met 1-Pro 150) was fused with a polyhistidine tag at the C-terminus.
Purity:
> 94 % as determined by SDS-PAGE
Mol Mass:
15.7 kDa
AP Mol Mass:
20-30 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
