PerCP/Cyanine5.5 Anti-Mouse CD62L Antibody [Mel14] (AGEL0641)

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SKU:
AGEL0641
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
Mel14
Conjugation:
PerCP/Cy5.5
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Mouse CD62L Antibody [Mel14]

The Mouse CD62L Monoclonal Antibody (PERCP/Cyanine5.5 Conjugated, Mel14) from Assay Genie is a cutting-edge tool designed for researchers studying immune cell subsets and migration patterns in mice. This monoclonal antibody specifically targets CD62L, a cell surface glycoprotein involved in lymphocyte homing and adhesion.With its PERCP/Cyanine5.5 conjugation, this antibody offers exceptional fluorescence detection capabilities, allowing for precise and sensitive analysis in flow cytometry applications. The Mel14 antibody recognizes the CD62L antigen with high affinity and specificity, making it a reliable choice for immunophenotyping studies in mouse models.

CD62L, also known as L-selectin, is crucial for the trafficking of lymphocytes to secondary lymphoid organs and sites of inflammation. By targeting CD62L with the Mel14 antibody, researchers can gain insights into immune cell migration patterns, activation status, and homing behaviors in various experimental settings.Whether investigating immune responses, inflammation, or autoimmune conditions, the Mouse CD62L Monoclonal Antibody (PERCP/Cyanine5.5 Conjugated, Mel14) offers a valuable tool for dissecting the intricate mechanisms of immune cell dynamics in mouse models. Trust Assay Genie for high-quality antibodies that empower your research endeavors.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD62L Antibody [Mel14]
SKU:AGEL0641
Size:25µg, 100µg
Clone No:Mel14
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P18337
Gene ID:20343
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

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