APC Anti-Mouse CD62L Antibody [Mel14] (AGEL0636)

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SKU:
AGEL0636
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
Mel14
Conjugation:
APC
Frequently bought together:

Description

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APC Anti-Mouse CD62L Antibody [Mel14]

The Mouse CD62L Monoclonal Antibody (APC Conjugated, MEL-14, AGEL0636) from Assay Genie is a powerful tool for immunology and cell biology research. This antibody is specifically designed for the detection and analysis of CD62L, a crucial cell surface molecule involved in lymphocyte migration and homing.Derived from a monoclonal antibody, this product offers high specificity and sensitivity in identifying CD62L in mouse samples. The APC conjugation enhances the detection signal, making it suitable for flow cytometry applications. Researchers can rely on the quality and consistency of this antibody for reliable results in their experiments.

CD62L, also known as L-selectin, plays a pivotal role in lymphocyte trafficking and immune response regulation. By targeting CD62L, researchers can gain insights into the mechanisms underlying immune cell migration and activation. This antibody opens up possibilities for investigating the role of CD62L in various physiological and pathological processes, including inflammation, infection, and immune-mediated diseases.Enhance your research capabilities with the Mouse CD62L Monoclonal Antibody (APC Conjugated, MEL-14, AGEL0636) from Assay Genie, and unravel the complexities of immune cell dynamics with precision and efficiency.

Product Title:APC Anti-Mouse CD62L Antibody [Mel14]
SKU:AGEL0636
Size:25µg, 100µg
Clone No:Mel14
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P18337
Gene ID:20343
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

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