PE/Cyanine5 Anti-Mouse CD54 Antibody [YN1/1.7.4] (AGEL0714)

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SKU:
AGEL0714
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
YN1/1.7.4
Conjugation:
PE/Cy5
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD54 Antibody [YN1/1.7.4]

The Mouse CD54 Monoclonal Antibody (PE/Cyanine5 Conjugated, YN1/1.7.4) is a high-quality antibody designed for research applications involving CD54, also known as intercellular adhesion molecule-1 (ICAM-1). This antibody, conjugated with PE/Cyanine5, is specifically designed to enable detection and analysis of CD54 in various cell types.CD54 is a cell surface glycoprotein involved in immune responses, inflammation, and cell adhesion processes. It plays a key role in leukocyte migration and interaction with endothelial cells during immune responses.

The Mouse CD54 Monoclonal Antibody is validated for use in flow cytometry applications, making it an excellent tool for studying mechanisms of cell adhesion, migration, and immune response regulation.Researchers in immunology, inflammation, and related fields will find the Mouse CD54 Monoclonal Antibody (PE/Cyanine5 Conjugated, YN1/1.7.4) to be a reliable reagent for their studies. Its specificity and sensitivity make it an essential tool for unraveling the intricate pathways involving CD54 in various biological processes.

Product Title:PE/Cyanine5 Anti-Mouse CD54 Antibody [YN1/1.7.4]
SKU:AGEL0714
Size:25µg, 100µg
Clone No:YN1/1.7.4
Synonyms:Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P13597
Gene ID:15894
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.

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