FITC Anti-Mouse CD54 Antibody [YN1/1.7.4] (AGEL0710)

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SKU:
AGEL0710
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
YN1/1.7.4
Conjugation:
FITC
Frequently bought together:

Description

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FITC Anti-Mouse CD54 Antibody [YN1/1.7.4]

The Mouse CD54 Monoclonal Antibody (FITC Conjugated) (YN1/1.7.4) (AGEL0710) offered by AssayGenie is a specialized tool for researchers studying CD54, also known as intercellular adhesion molecule 1 (ICAM-1). This antibody, generated from mouse sources, is conjugated with FITC for fluorescence detection applications. It is highly specific and suitable for use in flow cytometry and immunofluorescence assays to detect CD54 expression on cell surfaces.CD54, a key cell adhesion molecule, plays a crucial role in immune response regulation by mediating interactions between cells and facilitating immune cell trafficking.

Its involvement in inflammatory processes and immune cell activation makes it a valuable target for research in immunology, infectious diseases, and inflammatory disorders. The Mouse CD54 Monoclonal Antibody (FITC Conjugated) (YN1/1.7.4) provides researchers with a reliable tool for investigating CD54 functions in various biological contexts, aiding in the understanding of immune responses and potential therapeutic targets.

Product Title:FITC Anti-Mouse CD54 Antibody [YN1/1.7.4]
SKU:AGEL0710
Size:25µg, 100µg
Clone No:YN1/1.7.4
Synonyms:Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P13597
Gene ID:15894
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.

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