GenieFluor 488 Anti-Mouse CD54 Antibody [YN1/1.7.4] (AGEL0121)

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SKU:
AGEL0121
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
YN1/1.7.4
Conjugation:
AF 488
Applications:
FC
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD54 Antibody [YN1/1.7.4]

The Mouse CD54 Monoclonal Antibody (AG-EL0121) is an essential tool for researchers studying CD54, a cell adhesion molecule also known as intercellular adhesion molecule-1 (ICAM-1). This Alexa Fluor 488-conjugated antibody, clone YN1/1.7.4, is specifically designed for fluorescence-based applications, allowing for precise visualization and analysis of CD54 expression in various experimental setups.CD54/ICAM-1 plays a crucial role in mediating immune responses, facilitating leukocyte adhesion to endothelial cells and promoting inflammatory processes. The monoclonal antibody offered by Assay Genie is highly specific to mouse samples, providing researchers with a reliable tool for investigating CD54 expression levels and localization in different tissues and cell types.

Its conjugation with Alexa Fluor 488 further enhances its utility for fluorescence microscopy, flow cytometry, and other imaging techniques.With its proven efficacy and specificity, the Mouse CD54 Monoclonal Antibody (AG-EL0121) is a valuable resource for studies focusing on immune cell interactions, inflammation, and related disease processes. Researchers can leverage the antibody's capabilities to deepen their understanding of CD54 function and its potential implications in various pathological conditions, including autoimmune disorders, infectious diseases, and inflammatory disorders.

Product Title:GenieFluor 488 Anti-Mouse CD54 Antibody [YN1/1.7.4]
SKU:AGEL0121
Size:50 Tests, 100 Tests, 200 Tests
Clone No:YN1/1.7.4
Synonyms:Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P13597
Gene ID:15894
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.

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