The Mouse CD5 Monoclonal Antibody (PE/Cyanine7 Conjugated) 53-7.3 (AGEL1964) is a versatile tool designed for research involving CD5, a cell surface protein involved in immune regulation and T-cell activation. This monoclonal antibody, specifically conjugated with PE/Cyanine7, is raised in mice and exhibits high reactivity with mouse samples.CD5, also known as lymphocyte antigen 1 (Ly-1), is a crucial marker in the field of immunology, particularly for identifying and studying T-cell populations. The CD5 Monoclonal Antibody enables precise detection and analysis of CD5 expression in various cell types, making it an invaluable resource for investigations into immune responses, autoimmune diseases, and T-cell functionality.
With its specificity to CD5, researchers can utilize this antibody in flow cytometry and other immunological assays to deepen their understanding of T-cell biology and the role of CD5 in immune system regulation. By targeting CD5, this antibody facilitates detailed examination of T-cell subsets and their activation states, providing key insights for studies related to immune-mediated disorders and immunotherapy development.For researchers working in immunology, cell biology, and related fields, the Mouse CD5 Monoclonal Antibody (PE/Cyanine7 Conjugated) 53-7.3 (AGEL1964) offers a valuable resource for investigating the intricate mechanisms of T-cell function and immune system modulation.
Product Title:
PE/Cyanine7 Anti-Mouse CD5 Antibody [53-7.3]
SKU:
AGEL1964
Size:
25µg, 100µg
Clone No:
53-7.3
Synonyms:
Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 7
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.