The Mouse CD5 Monoclonal Antibody PE-Cyanine5 Conjugated (53-7.3) (AGEL1963) is a powerful tool for researchers studying CD5, a cell surface glycoprotein involved in T cell activation and regulation. This monoclonal antibody, specific to mouse samples, is conjugated with PE-Cyanine5 for optimal detection and analysis in flow cytometry and immunofluorescence applications.CD5 is a key marker for T lymphocytes and plays a pivotal role in T cell signaling and activation. Its expression pattern can provide insights into T cell development, differentiation, and function in the immune system.
Researchers studying immunology, autoimmunity, and lymphocyte biology can benefit from the precise targeting and detection capabilities of the Mouse CD5 Monoclonal Antibody PE-Cyanine5 Conjugated (53-7.3) (AGEL1963).By enabling the specific detection of CD5 in mouse samples, this antibody facilitates detailed investigations into T cell behavior and function in various experimental settings. Its high specificity and sensitivity make it an essential tool for unraveling the complexities of immune responses and exploring therapeutic targets related to T cell-mediated diseases.
Product Title:
PE/Cyanine5 Anti-Mouse CD5 Antibody [53-7.3]
SKU:
AGEL1963
Size:
25µg, 100µg
Clone No:
53-7.3
Synonyms:
Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.
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