The Mouse CD5 Monoclonal Antibody PE-Cyanine5 Conjugated (53-7.3) is a valuable tool for immune system research, designed for detecting and analyzing the CD5 protein on cell surfaces. This monoclonal antibody, labeled with PE-Cyanine5, offers high specificity and sensitivity in flow cytometry applications. CD5, a well-known marker of T cells and B-1a cells, plays a crucial role in immune cell signaling and activation.The 53-7.3 antibody is suitable for investigating the expression and function of CD5 in various cell populations, making it ideal for immunology studies and understanding immune responses in health and disease.
With its precise binding ability, researchers can explore the involvement of CD5 in immune cell development, activation, and tolerance mechanisms. This antibody is a valuable asset for scientists studying the complexities of the immune system and its role in diseases such as autoimmune disorders and cancer.
Product Title:
PE/Cyanine5 Anti-Mouse CD5 Antibody [53-7.3]
SKU:
AGEL1954
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
53-7.3
Synonyms:
Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.