PE Anti-Mouse CD5 Antibody [53-7.3] (AGEL1961)

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SKU:
AGEL1961
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
53-7.3
Conjugation:
PE
Frequently bought together:

Description

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PE Anti-Mouse CD5 Antibody [53-7.3]

The Mouse CD5 Monoclonal Antibody PE Conjugated (53-7.3) is a specialized tool for researchers studying CD5, a crucial cell surface glycoprotein involved in lymphocyte development and activation. This monoclonal antibody, conjugated with PE for fluorescent detection, is specifically engineered for flow cytometry applications in mouse samples.CD5, a member of the scavenger receptor cysteine-rich superfamily, is predominantly expressed on T cells and B-1a cells, where it regulates signaling pathways associated with cell activation and tolerance. Its unique role in modulating immune responses and promoting self-tolerance makes it a key target in immunology research, particularly in understanding autoimmune diseases, B cell malignancies, and immune system dysregulation.

By utilizing the Mouse CD5 Monoclonal Antibody PE Conjugated (53-7.3), researchers can accurately detect and analyze CD5 expression on different immune cell subsets, enabling deeper insights into immune system function and dysfunction. This antibody is a valuable asset in elucidating the complexities of immune modulation and holds promise for advancing therapeutic strategies targeting CD5-mediated pathways in various disease contexts.

Product Title:PE Anti-Mouse CD5 Antibody [53-7.3]
SKU:AGEL1961
Size:25µg, 100µg
Clone No:53-7.3
Synonyms:Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P13379
Gene ID:12507
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.

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