The Mouse CD5 Monoclonal Antibody (AF647 conjugated, clone 53-7.3) is a specialized research tool offered by AssayGenie. This antibody is specifically designed for the detection and analysis of CD5, a cell surface glycoprotein expressed on T cells, B cells, and thymocytes. The monoclonal antibody, conjugated with AF647 for fluorescence detection, provides a powerful tool for immunofluorescence assays, flow cytometry, and fluorescence microscopy applications.CD5 plays a pivotal role in regulating immune responses and modulating signaling pathways in lymphocytes. By targeting CD5, researchers can gain valuable insights into the function and activation of lymphocyte subsets, aiding in the investigation of immune processes, autoimmune diseases, and lymphoid malignancies.
The AF647-conjugated Mouse CD5 Monoclonal Antibody (clone 53-7.3) offers high specificity and sensitivity for detecting CD5 expression in various cell types, making it an essential reagent for immunology and cancer research studies.For scientists looking to delve deeper into the intricate mechanisms of immune regulation and lymphocyte function, the Mouse CD5 Monoclonal Antibody (AF647 conjugated, clone 53-7.3) from AssayGenie provides a reliable and versatile tool for advanced research applications.
Product Title:
GenieFluor 647 Anti-Mouse CD5 Antibody [53-7.3]
SKU:
AGEL1968
Size:
25µg, 100µg
Clone No:
53-7.3
Synonyms:
Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.
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