The Mouse CD5 Monoclonal Antibody (AF647 Conjugated) (Clone 53-7.3) is a valuable tool for research involving the CD5 protein, a cell surface marker found on T cells and B-1a cells. This antibody, conjugated with AF647 for efficient detection in flow cytometry and immunofluorescence assays, is ideal for studying immune cell populations and their interactions.CD5 plays a crucial role in modulating immune responses, including T cell activation and tolerance induction. By targeting CD5, researchers can gain insights into immune cell function and potential therapeutic interventions for autoimmune diseases, lymphomas, and other immune-related disorders.
This monoclonal antibody, validated for specificity and sensitivity, offers reliable results in experimental settings, making it a valuable asset for immunologists, oncologists, and researchers studying immune system functionality. Explore the intricate mechanisms of immune regulation with the Mouse CD5 Monoclonal Antibody (AF647 Conjugated) (Clone 53-7.3) and advance your research into immunology and cancer biology.
Product Title:
GenieFluor 647 Anti-Mouse CD5 Antibody [53-7.3]
SKU:
AGEL1959
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
53-7.3
Synonyms:
Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.
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