The Mouse CD5 Monoclonal Antibody (AF488 Conjugated) 53-7.3 (AGEL1958) offered by AssayGenie is a cutting-edge tool designed for research applications involving CD5, a cell surface glycoprotein found on T cells. This monoclonal antibody, conjugated with AF488 for fluorescence-based detection, is highly specific and reactive with mouse samples. It has been rigorously validated for various experimental techniques, including flow cytometry and immunofluorescence, enabling precise detection and analysis of CD5 expression in different cell populations.CD5, a well-known marker of mature T cells, plays a pivotal role in T cell development and activation, as well as in regulating immune responses.
Its importance in modulating T cell signaling and function makes it a key target for investigating immune system dynamics in health and disease. Research utilizing the Mouse CD5 Monoclonal Antibody (AF488 Conjugated) 53-7.3 (AGEL1958) can provide valuable insights into T cell biology, immune regulation, and potential therapeutic strategies for conditions involving aberrant T cell activity, such as autoimmune diseases and immune-related disorders.
Product Title:
GenieFluor 488 Anti-Mouse CD5 Antibody [53-7.3]
SKU:
AGEL1958
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
53-7.3
Synonyms:
Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.
![GenieFluor 488 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1958)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/608x608/products/122348/120528/geniefluor-488-anti-mouse-cd5-antibody-53-7.3-agel1958__51786__56174.1732016546.jpg?c=1 "GenieFluor 488 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1958)")
![GenieFluor 488 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1958)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/1280x1280/products/122348/120528/geniefluor-488-anti-mouse-cd5-antibody-53-7.3-agel1958__51786__56174.1732016546.jpg?c=1&imbypass=on "GenieFluor 488 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1958)")
![GenieFluor 488 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1967)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/122356/120536/geniefluor-488-anti-mouse-cd5-antibody-53-7.3-agel1967__96008__65421.1732016551.jpg?c=1 "GenieFluor 488 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1967)")
![GenieFluor 647 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1959)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/122349/120529/geniefluor-647-anti-mouse-cd5-antibody-53-7.3-agel1959__09532__76520.1732016547.jpg?c=1 "GenieFluor 647 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1959)")
![GenieFluor 647 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1968)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/122357/120537/geniefluor-647-anti-mouse-cd5-antibody-53-7.3-agel1968__93819__69204.1732016551.jpg?c=1 "GenieFluor 647 Anti-Mouse CD5 Antibody [53-7.3] (AGEL1968)")
![FITC Anti-Mouse CD5 Antibody [53-7.3] (AGEL1951)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/122343/120523/fitc-anti-mouse-cd5-antibody-53-7.3-agel1951__67324__69505.1732016544.jpg?c=1 "FITC Anti-Mouse CD5 Antibody [53-7.3] (AGEL1951)")
![PE Anti-Mouse CD5 Antibody [53-7.3] (AGEL1961)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/122351/120531/pe-anti-mouse-cd5-antibody-53-7.3-agel1961__09480__32329.1732016547.jpg?c=1 "PE Anti-Mouse CD5 Antibody [53-7.3] (AGEL1961)")