PerCP/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5] (AGEL1443)

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SKU:
AGEL1443
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
DX5
Conjugation:
PerCP/Cy5.5
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5]

The Mouse CD49b Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, DX5, AGEL1443) is a powerful tool for researchers studying immune cell populations and their interactions. This antibody specifically targets CD49b, a cell surface marker found on natural killer cells and a subset of T cells. By binding to CD49b, this antibody allows for the identification and analysis of these specific cell populations in various assays, including flow cytometry.CD49b, also known as DX5 antigen, is a crucial molecule involved in the activation and function of natural killer cells, which play a vital role in the immune response against tumors and virally infected cells.

By targeting CD49b, researchers can gain valuable insights into the role of natural killer cells in immune surveillance and anti-tumor immunity.The conjugation of PerCP-Cyanine5.5 to this antibody enhances its utility in flow cytometry applications, providing researchers with a reliable tool for multiparameter analysis of immune cell subsets. With its high specificity and sensitivity, the Mouse CD49b Monoclonal Antibody is an essential reagent for studies focused on understanding the role of natural killer cells and T cell subsets in immune responses, cancer immunology, and infectious diseases.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL1443
Size:50 Tests, 100 Tests, 200 Tests
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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