PE/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5] (AGEL1442)

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SKU:
AGEL1442
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5]

The Mouse CD49b Monoclonal Antibody PE-Cyanine5.5 Conjugated (DX5) (AGEL1442) is a cutting-edge tool designed for researchers studying immune cells, particularly natural killer (NK) cells. This antibody, a monoclonal antibody raised against the CD49b antigen, is highly specific and suitable for flow cytometry and cell sorting applications.CD49b, also known as DX5, is a marker predominantly expressed on NK cells in mice and plays a crucial role in their function and activity. By targeting CD49b, researchers can effectively identify, isolate, and study NK cells in various experimental settings, including immunology, oncology, and infectious disease research.

With its high sensitivity and specificity, the Mouse CD49b Monoclonal Antibody PE-Cyanine5.5 Conjugated (DX5) (AGEL1442) offers researchers a reliable tool for characterizing NK cells in diverse biological samples. Its application extends to exploring immune responses, investigating NK cell-mediated cytotoxicity, and understanding the role of NK cells in disease pathogenesis. Harnessing the power of this antibody opens up new avenues for advancing our knowledge of immune cell biology and developing targeted therapeutic strategies in the field of immunology and beyond.

Product Title:PE/Cyanine5.5 Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL1442
Size:50 Tests, 100 Tests, 200 Tests
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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