APC Anti-Mouse CD49b Antibody [DX5] (AGEL1447)

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SKU:
AGEL1447
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
DX5
Conjugation:
APC
Frequently bought together:

Description

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APC Anti-Mouse CD49b Antibody [DX5]

The Mouse CD49b Monoclonal Antibody (APC Conjugated, DX5, AGEL1447) offered by AssayGenie is a valuable tool for researchers studying immune cell populations in mice. This antibody specifically targets the CD49b antigen, also known as DX5, which is commonly used as a marker for natural killer (NK) cells and a subset of T cells in mice.By utilizing this APC-conjugated monoclonal antibody, researchers can accurately identify and isolate CD49b-positive cells for further analysis in flow cytometry and other immunological assays.

The high specificity and sensitivity of this antibody make it an essential reagent for investigating the roles of NK cells and CD49b-expressing T cells in immune responses, infectious diseases, cancer immunology, and autoimmune disorders in mouse models.With its reliable performance and consistency, the Mouse CD49b Monoclonal Antibody (APC Conjugated, DX5, AGEL1447) from AssayGenie ensures accurate and reproducible results, facilitating breakthroughs in immunology research and drug development.

Product Title:APC Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL1447
Size:25µg, 100µg
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:APC Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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