The Mouse CD48 Monoclonal Antibody (FITC Conjugated, HM48-1) provided by AssayGenie (Product Code: AGL0695) is an essential tool for researchers studying CD48, a transmembrane protein involved in immune responses and antigen presentation. This monoclonal antibody, designed for use in flow cytometry and immunofluorescence applications, specifically targets mouse CD48 and enables precise detection and analysis in various experimental settings.CD48, also known as BCM1 (B-lymphocyte activation marker), is a cell surface glycoprotein that plays a crucial role in mediating immune cell interactions and regulating immune responses. By binding to CD48, the HM48-1 monoclonal antibody allows researchers to investigate CD48 expression levels, distribution patterns, and functional roles in immune cells, making it a valuable resource for immunologists, cell biologists, and cancer researchers.
The FITC conjugation of this monoclonal antibody provides enhanced sensitivity and brightness, allowing for reliable and accurate detection of CD48 in flow cytometry experiments. Its high specificity and low background make it a versatile tool for investigating mouse CD48 expression in different cell types and biological samples, furthering our understanding of immune cell signaling and communication mechanisms.Overall, the Mouse CD48 Monoclonal Antibody (FITC Conjugated, HM48-1) from AssayGenie is a powerful research reagent that can facilitate cutting-edge studies in immunology, cancer biology, and beyond. Whether investigating immune cell interactions, studying antigen presentation pathways, or exploring immunomodulatory mechanisms, this antibody is sure to provide valuable insights and support diverse research endeavors.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P18181
Gene ID:
12506
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 45 kD GPI-anchored glycoprotein also known as BCM1, Blast-1 (human), and OX-45 (rat). It is a member of the Ig superfamily, expressed on T and B cells and monocytes/macrophages. It plays a role in adhesion and T cell recognition. The primary ligands for CD48 are CD2 and CD244.