The Mouse CD48 Monoclonal Antibody (APC conjugated) HM48-1 (AGEL0697) is a vital tool for researchers investigating CD48, a key cell surface protein involved in immune response regulation. This monoclonal antibody, engineered for specificity and sensitivity, is uniquely designed to target CD48 in mouse samples, facilitating detailed analysis and detection in a variety of experimental settings.CD48, a glycoprotein belonging to the immunoglobulin superfamily, is integral to immune cell interactions and signaling processes. Its role in modulating immune responses, particularly in regulating T cell activation and cytokine production, underscores its importance in immunology research and understanding immune-mediated diseases.
The HM48-1 antibody, conjugated with APC for enhanced detection capabilities, provides a reliable tool for accurately studying CD48 expression levels and localization within different cell populations.From investigating immune cell communication to exploring the impacts of CD48 dysregulation in disease states such as autoimmunity and infection, this monoclonal antibody is a valuable asset for unraveling the complexities of immune system function. Researchers can leverage its specificity and high affinity to uncover new insights into the role of CD48 in immune modulation, paving the way for innovative therapeutic approaches and targeted interventions in various immune-related disorders.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P18181
Gene ID:
12506
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 45 kD GPI-anchored glycoprotein also known as BCM1, Blast-1 (human), and OX-45 (rat). It is a member of the Ig superfamily, expressed on T and B cells and monocytes/macrophages. It plays a role in adhesion and T cell recognition. The primary ligands for CD48 are CD2 and CD244.