The Mouse CD48 Monoclonal Antibody (APC Conjugated) (HM48-1) is a vital tool for researchers studying CD48, a cell surface protein involved in immune system functions and cell signaling pathways. This antibody, derived from mouse hybridoma cells, is conjugated with APC for easy detection and analysis in flow cytometry and other related applications. By specifically targeting the CD48 molecule, this antibody allows for precise identification and characterization of CD48 expression in various cell populations, making it a valuable asset in immunology and cell biology research.CD48, a member of the CD2 subfamily of immunoglobulin superfamily molecules, plays important roles in immune response modulation, cell adhesion, and communication between immune cells.
Understanding the functions and interactions of CD48 is essential for unraveling its implications in diseases like autoimmune disorders, infectious diseases, and cancer. By utilizing the Mouse CD48 Monoclonal Antibody (APC Conjugated) (HM48-1), researchers can delve deeper into the mechanisms involving CD48 and potentially discover new therapeutic targets or diagnostic markers for immune-related disorders.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P18181
Gene ID:
12506
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 45 kD GPI-anchored glycoprotein also known as BCM1, Blast-1 (human), and OX-45 (rat). It is a member of the Ig superfamily, expressed on T and B cells and monocytes/macrophages. It plays a role in adhesion and T cell recognition. The primary ligands for CD48 are CD2 and CD244.