The Mouse CD48 Monoclonal Antibody (Alexa Fluor 488 Conjugated) HM48-1 (AGEL0114) is a cutting-edge tool designed for researchers studying CD48, a cell surface protein involved in immune responses and cell signaling pathways. This monoclonal antibody, conjugated with Alexa Fluor 488 for fluorescent detection, offers high specificity and sensitivity in various experimental applications.CD48 is known to play a pivotal role in immune cell interactions, including T cell activation and response to antigens. By targeting CD48 with this monoclonal antibody, researchers can investigate its functions and associated signaling pathways in detail. The conjugation with Alexa Fluor 488 further enhances the versatility of this antibody for fluorescence-based assays, imaging, and flow cytometry analyses.
With its robust reactivity in mouse samples and validation for specific techniques such as immunofluorescence, this antibody is an invaluable asset for studies focusing on immune system function, immunology, and molecular pathways involved in immune regulation. By using the Mouse CD48 Monoclonal Antibody (Alexa Fluor 488 Conjugated) HM48-1 (AGEL0114), researchers can gain deeper insights into the mechanisms underlying immune responses and potentially discover novel therapeutic targets for immune-related disorders and diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P18181
Gene ID:
12506
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 45 kD GPI-anchored glycoprotein also known as BCM1, Blast-1 (human), and OX-45 (rat). It is a member of the Ig superfamily, expressed on T and B cells and monocytes/macrophages. It plays a role in adhesion and T cell recognition. The primary ligands for CD48 are CD2 and CD244.