The Mouse CD48 Monoclonal Antibody (AF488 Conjugated, HM48-1) is a cutting-edge tool for researchers investigating CD48, a cell surface protein involved in immune response modulation. This high-quality antibody, derived from mouse hybridoma cells, exhibits exceptional reactivity in a wide range of applications, particularly fluorescence microscopy and flow cytometry. By specifically binding to CD48, this antibody enables precise detection and analysis of this important molecule in various biological samples.CD48, a member of the CD2 family of proteins, serves as a key regulator of immune cell activation and communication. Its role in modulating signaling pathways and immune cell interactions makes it a crucial player in immune surveillance, inflammation, and various disease processes.
Research focusing on CD48 opens up opportunities to gain insights into immune system dynamics, autoimmune disorders, and inflammatory conditions, paving the way for the development of novel therapeutic approaches targeting CD48-mediated pathways.With its unique capabilities and specificity, the Mouse CD48 Monoclonal Antibody (AF488 Conjugated, HM48-1) is an invaluable asset for studies in immunology, cancer biology, and beyond. By harnessing the power of this antibody, researchers can delve deeper into the complexities of CD48 function and its impact on immune responses, ultimately advancing our understanding of immune-related diseases and guiding the development of targeted interventions for improved patient outcomes.
Genie Fluor 488 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P18181
Gene ID:
12506
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 45 kD GPI-anchored glycoprotein also known as BCM1, Blast-1 (human), and OX-45 (rat). It is a member of the Ig superfamily, expressed on T and B cells and monocytes/macrophages. It plays a role in adhesion and T cell recognition. The primary ligands for CD48 are CD2 and CD244.