PerCP/Cyanine5.5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL1406)

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SKU:
AGEL1406
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
RA3.3A 1/6.1
Conjugation:
PerCP/Cy5.5
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R (B220) Monoclonal Antibody - PERCP Cyanine5.5 Conjugated (RA3-6B2) is an essential tool for researchers studying B cells in murine models. This highly specific antibody recognizes the CD45R (B220) antigen, a cell surface marker predominantly expressed on B lymphocytes, making it a valuable reagent for immunophenotyping and tracking B cell populations in experimental settings.With its PERCP Cyanine5.5 conjugation, this antibody offers enhanced fluorescence for flow cytometry applications, allowing for precise detection and analysis of B220-positive cells in complex biological samples.

Its monoclonal origin ensures batch-to-batch consistency and high specificity, contributing to reliable and reproducible experimental results.The CD45R (B220) Monoclonal Antibody is a versatile tool for investigating B cell development, differentiation, and functions in various research areas, including immunology, cancer biology, and autoimmune diseases. Its ability to target specific B cell subsets enables researchers to delve deeper into the intricate mechanisms governing B cell biology, paving the way for new insights and discoveries in the field.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL1406
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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