PerCP Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL1403)

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SKU:
AGEL1403
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
RA3.3A 1/6.1
Conjugation:
PerCP
Frequently bought together:

Description

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PerCP Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R/B220 Monoclonal Antibody (PE/CY7 conjugated, RA3-6B2) is an essential tool for studying the CD45R/B220 surface marker in mouse samples. This antibody, clone RA3-6B2, is highly specific and has been conjugated with PE/CY7 for easy detection in flow cytometry applications. CD45R, also known as B220, is a commonly used marker for identifying B cells and subsets of T cells in mice. Its expression pattern is crucial for understanding immune cell development, activation, and differentiation. The RA3-6B2 antibody is validated for its utility in flow cytometry and immunophenotyping studies, enabling precise identification and characterization of B cells in various mouse models.

Researchers interested in immunology, hematopoiesis, and autoimmune diseases will find the Mouse CD45R/B220 Monoclonal Antibody (PE/CY7 conjugated, RA3-6B2) to be a valuable tool for their studies. Its high specificity and reliability make it an indispensable reagent for investigating the role of CD45R/B220-expressing cells in immune responses and disease pathogenesis.

Product Title:PerCP Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL1403
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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