PE/Cyanine7 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL1413)

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SKU:
AGEL1413
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R/B220 Monoclonal Antibody (PE-Cyanine7 Conjugated) - RA3-3A1-6.1 (AGEL1413) offered by Assay Genie is a highly specific antibody designed for research applications involving the CD45R/B220 protein in mouse samples. This monoclonal antibody is conjugated with PE-Cyanine7, providing a fluorescent marker for easy detection and visualization of CD45R/B220-expressing cells.CD45R, also known as B220, is a common marker used to identify B cells and subsets of T cells in the immune system. The RA3-3A1-6.1 antibody specifically targets CD45R/B220, making it a valuable tool for studying B cell development, activation, and function in immunology research. The PE-Cyanine7 conjugation enhances the antibody's utility in flow cytometry and fluorescence-based assays, enabling high-resolution analysis of B cell populations in experimental settings.

With its reliable specificity and fluorescent labeling, the Mouse CD45R/B220 Monoclonal Antibody (PE-Cyanine7 Conjugated) - RA3-3A1-6.1 (AGEL1413) from Assay Genie is a versatile reagent for researchers studying B cell biology, immune responses, and related diseases in mouse models. By facilitating precise detection and characterization of CD45R/B220-expressing cells, this antibody supports in-depth investigations into the role of B cells in immune regulation and pathogenesis, offering valuable insights for therapeutic targeting and drug development in various immunological disorders and conditions.

Product Title:PE/Cyanine7 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL1413
Size:25µg, 100µg
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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