PE/Cyanine5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL0424)

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SKU:
AGEL0424
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgM
Clone:
RA3.3A 1/6.1
Conjugation:
PE/Cy5
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The Mouse CD45R/B220 Monoclonal Antibody PE-Cy5 Conjugated (RA3-6B2) is a valuable tool for research involving immune cell identification and isolation in mouse models. This monoclonal antibody specifically targets the CD45R/B220 antigen, a cell surface marker commonly used to identify B cells, and is conjugated with PE-Cy5 for efficient detection in flow cytometry applications.CD45R/B220 is a well-characterized marker for B cells in mice, playing a crucial role in their development, activation, and differentiation. By using the RA3-6B2 antibody, researchers can accurately identify and analyze B cell populations in various tissues and explore their roles in immune responses, autoimmune diseases, and infectious conditions.

This monoclonal antibody is highly specific and provides reliable results in experimental settings, making it an essential tool for immunologists, cancer researchers, and those studying B cell biology. Its conjugation with PE-Cy5 allows for enhanced detection sensitivity and multiparametric analysis, aiding in the comprehensive characterization of immune cell subsets.For researchers delving into the intricacies of mouse immunology and seeking to elucidate the functions of B cells in health and disease, the Mouse CD45R/B220 Monoclonal Antibody PE-Cy5 Conjugated (RA3-6B2) is a key reagent that facilitates precise and accurate detection of CD45R/B220-expressing B cells in experimental models.

Product Title:PE/Cyanine5 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL0424
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:PE/Cyanine5 Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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