The Mouse CD45 Monoclonal Antibody (PE-Cyanine5 Conjugated, 30-F11, AGEL1671) is a cutting-edge tool designed for precise detection and analysis of the CD45 antigen in mouse samples. CD45, also known as leukocyte common antigen, is a crucial cell surface marker widely used in immunology and hematopoietic research for identifying different immune cell populations.This monoclonal antibody, conjugated with PE-Cyanine5 for enhanced visualization and quantification, offers high specificity and sensitivity in various experimental applications, including flow cytometry and immunofluorescence. Its compatibility with mouse samples ensures reliable and accurate results, making it an essential reagent for immunologists, cell biologists, and researchers studying immune responses in mouse models.
By targeting the CD45 antigen, this antibody enables researchers to analyze immune cell populations, monitor immune responses, and investigate the role of leukocytes in various physiological and pathological processes. Its versatility and precision make it a valuable asset for studies focused on immune system function, inflammatory diseases, infectious disorders, and immunotherapy development.Trust the Mouse CD45 Monoclonal Antibody (PE-Cyanine5 Conjugated, 30-F11, AGEL1671) to elevate your research and unlock new insights into the dynamic world of immune cell biology and immunological processes in mouse models.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06800
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.