The Mouse CD45.2 Monoclonal Antibody (PE/Cyanine5 Conjugated), 104-2 (AGEL1529), offered by Assay Genie, is a powerful tool for researchers studying the immune system and hematopoietic cells in mice. This antibody specifically targets CD45.2, a cell surface protein known for its role in immune cell development and activation.With its PE/Cyanine5 conjugation, this antibody allows for easy detection and analysis of CD45.2 in flow cytometry applications, providing researchers with valuable insights into immune cell populations and responses. Its high specificity and sensitivity make it a reliable reagent for experiments requiring precise identification and quantification of CD45.2-expressing cells.
The CD45.2 Monoclonal Antibody is ideal for use in a wide range of research areas, including immunology, cancer biology, and infectious diseases. By targeting CD45.2, researchers can investigate immune cell subsets, immune responses to pathogens, and the development of immune-based therapies.Overall, the Mouse CD45.2 Monoclonal Antibody (PE/Cyanine5 Conjugated), 104-2 (AGEL1529), from Assay Genie is a valuable asset for scientists seeking to advance their understanding of immune function and hematopoiesis in mouse models. Its high quality and performance ensure reliable and reproducible results, making it an essential tool for cutting-edge research in the field of immunology.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
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