APC Anti-Mouse CD45.2 Antibody [104.2] (AGEL1517)

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SKU:
AGEL1517
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
104.2
Conjugation:
APC
Frequently bought together:

Description

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APC Anti-Mouse CD45.2 Antibody [104.2]

The Mouse CD45.2 Monoclonal Antibody (APC-conjugated) 104-2 (AGEL1517) is a specialized tool for researchers studying mouse immune cells, particularly focusing on the CD45.2 protein. This monoclonal antibody, conjugated to APC for enhanced fluorescent detection, offers high specificity and sensitivity in detecting mouse CD45.2 in various experimental settings.CD45.2 is a transmembrane glycoprotein expressed on most leukocytes, serving as a crucial marker for immune cell identification and characterization. By targeting CD45.2, researchers can gain valuable insights into immune cell populations, activation status, and migration patterns. This antibody facilitates flow cytometry analysis, immunofluorescence staining, and other immunological techniques for in-depth exploration of mouse immune responses.

With its validated performance and specificity for CD45.2, this antibody is pivotal in elucidating the roles of immune cells in disease, infection, and immunotherapy research. Its application extends to studies on inflammation, autoimmune disorders, infectious diseases, and cancer immunology, providing a versatile tool for investigating immune system dynamics in diverse biological contexts. Unlock the potential of your research by utilizing the Mouse CD45.2 Monoclonal Antibody (APC-conjugated) 104-2 (AGEL1517) for precise and reliable detection of mouse CD45.2 in your experimental assays.

Product Title:APC Anti-Mouse CD45.2 Antibody [104.2]
SKU:AGEL1517
Size:50 Tests, 100 Tests, 200 Tests
Clone No:104.2
Synonyms:Ly-5.2; LCA;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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