PE Anti-Mouse CD41 Antibody [MWReg30] (AGEL1943)

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SKU:
AGEL1943
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE Anti-Mouse CD41 Antibody [MWReg30]

The Mouse CD41 Monoclonal Antibody PE-Conjugated (MWReg30) is a vital tool for researchers studying CD41, a marker associated with platelet function and megakaryocyte differentiation. This antibody, derived from mouse hybridoma cells, specifically targets the CD41 antigen and is conjugated with PE for enhanced detection in flow cytometry experiments. Its high specificity and sensitivity make it an excellent choice for investigating platelet biology, thrombosis, and hematopoiesis in both basic research and clinical applications.CD41, also known as integrin alpha IIb, is a key component of the platelet surface receptor complex involved in blood clot formation and hemostasis.

Understanding the role of CD41 in these processes is essential for advancing our knowledge of cardiovascular diseases, bleeding disorders, and thrombotic events. By utilizing the Mouse CD41 Monoclonal Antibody PE-Conjugated (MWReg30), researchers can gain valuable insights into the function and regulation of CD41, paving the way for innovative diagnostic and therapeutic strategies in the field of hematology.

Product Title:PE Anti-Mouse CD41 Antibody [MWReg30]
SKU:AGEL1943
Size:25µg, 100µg
Clone No:MWReg30
Synonyms:Itga2b;GPalpha Iib;CD41;GPIIb;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QUM0
Gene ID:16399
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.

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