APC Anti-Mouse CD41 Antibody [MWReg30] (AGEL1944)

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SKU:
AGEL1944
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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APC Anti-Mouse CD41 Antibody [MWReg30]

The Mouse CD41 Monoclonal Antibody (APC Conjugated) MWReg30 (agEL1944) is a specialized antibody designed for research applications involving the CD41 protein, a key cell surface marker found on platelets and megakaryocytes. This monoclonal antibody, produced for use in mouse samples, is conjugated to allophycocyanin (APC) for easy visualization and detection in flow cytometry experiments.CD41, also known as integrin alpha IIb, is essential for platelet aggregation and thrombus formation, making it a critical player in hemostasis and vascular health. By targeting the CD41 protein, researchers can study platelet function, investigate megakaryocyte development, and explore disorders related to blood clotting and bleeding.

This APC-conjugated mouse CD41 monoclonal antibody, MWReg30 (agEL1944), offers high specificity and sensitivity for detecting CD41 expression in various cell types and tissues. Its suitability for flow cytometry analysis makes it a valuable tool for investigating thrombopoiesis, platelet-related disorders, and hematological conditions. Researchers in the fields of hematology, thrombosis, and vascular biology will find this antibody essential for their studies on platelet biology and related diseases.

Product Title:APC Anti-Mouse CD41 Antibody [MWReg30]
SKU:AGEL1944
Size:25µg, 100µg
Clone No:MWReg30
Synonyms:Itga2b;GPalpha Iib;CD41;GPIIb;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:APC Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QUM0
Gene ID:16399
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.

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