PerCP/Cyanine5.5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0779)

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SKU:
AGEL0779
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
FGK4.5/FGK45
Conjugation:
PerCP/Cy5.5
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (FGK4.5) is a specialized tool designed for research applications involving the CD40 molecule, a key regulator of immune responses. This antibody, conjugated to PerCP-Cyanine5.5, is specifically tailored for flow cytometry analysis, enabling precise detection of CD40 expression on cell surfaces. Its high reactivity and specificity to mouse samples make it an invaluable asset for immunologists and researchers studying immune cell activation and signaling pathways.CD40, a member of the tumor necrosis factor receptor superfamily, plays a crucial role in the regulation of immune responses by mediating interactions between immune cells. Its involvement in various immune processes, such as B-cell activation, antigen presentation, and cytokine production, underscores its importance in both innate and adaptive immunity.

By targeting CD40 with this monoclonal antibody, researchers can gain deep insights into the function and role of CD40 in different experimental models, providing a foundation for understanding immune regulation and developing therapeutic strategies for immune-related disorders.The FGK4.5 Monoclonal Antibody is a powerful tool that enhances the study of immune responses and inflammatory pathways by enabling precise labeling and detection of CD40 molecules on mouse cells. Its conjugation to PerCP-Cyanine5.5 ensures bright and stable fluorescence signals, facilitating accurate flow cytometry analysis and cell sorting. Whether investigating immune cell activation, vaccine development, or autoimmune diseases, this antibody offers researchers a reliable and specific solution for analyzing CD40 expression in a mouse model system.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0779
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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