PE/Cyanine5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0785)

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SKU:
AGEL0785
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
FGK4.5/FGK45
Conjugation:
PE/Cy5
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody PE-Cyanine5 Conjugated (FGK4.5 (FGK45)) is a cutting-edge research tool designed for the detection and analysis of CD40, a crucial cell surface receptor involved in immune regulation and activation. This monoclonal antibody, conjugated with PE-Cyanine5, offers high specificity and sensitivity for CD40 detection in various cell types and tissue samples.CD40 is known for its role in mediating immune responses, particularly in the activation of antigen-presenting cells and the regulation of T-cell function. Research involving CD40 has broad implications in immunology, oncology, and autoimmune diseases, making this antibody an essential tool for studying immune pathways and developing novel therapeutic interventions.

By targeting CD40 with precision and efficiency, this antibody enables researchers to investigate the intricate mechanisms of immune signaling and immune cell interactions. Its conjugation with PE-Cyanine5 allows for easy visualization and quantification of CD40 expression, facilitating detailed analysis in experimental settings.Whether exploring immune responses in cancer progression, autoimmune disorders, or infectious diseases, the Mouse CD40 Monoclonal Antibody PE-Cyanine5 Conjugated (FGK4.5 (FGK45)) offers unparalleled performance and reliability for researchers striving to unravel the complexities of immune regulation and immune-mediated pathologies.

Product Title:PE/Cyanine5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0785
Size:25µg, 100µg
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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