PE/Cyanine5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0776)

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SKU:
AGEL0776
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
FGK4.5/FGK45
Conjugation:
PE/Cy5
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (PE/Cyanine5 Conjugated, FGK4.5/FGK45, AGEL0776) is a powerful tool for research aimed at understanding the role of CD40 in immune responses and inflammatory processes. This antibody, a member of the CD40 molecule family, is specifically engineered for detecting and analyzing the CD40 protein in various cell types.CD40 is a key cell surface receptor involved in immune signaling, particularly in the activation of B cells and antigen-presenting cells. By targeting this receptor with the Mouse CD40 Monoclonal Antibody, researchers can gain valuable insights into the mechanisms underlying immune responses, immune activation, and immune modulation.

With its PE/Cyanine5 conjugation, this antibody offers the dual benefits of fluorescence detection and specificity for the CD40 protein, facilitating precise and reliable analysis of CD40 expression in experimental settings. Whether investigating immune system function, inflammatory diseases, or developing immunotherapies, the Mouse CD40 Monoclonal Antibody is an essential tool for advancing our understanding of immune regulation and potential therapeutic interventions.Order the Mouse CD40 Monoclonal Antibody (PE/Cyanine5 Conjugated, FGK4.5/FGK45, AGEL0776) today and enhance your research capabilities in immunology, cancer biology, and related fields.

Product Title:PE/Cyanine5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0776
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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