PE/Cyanine5.5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0787)

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SKU:
AGEL0787
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (PE/Cyanine5.5 Conjugated, FGK4.5, FGK45) - AGEL0787 is a specialized reagent designed for precise detection and analysis of CD40, a cell surface protein with key roles in immune activation and signaling pathways. This monoclonal antibody is derived from mouse hybridoma cultures and is conjugated with PE/Cyanine5.5 for easy visualization in flow cytometry and immunofluorescence studies.CD40 is a vital immune receptor involved in B cell activation, T cell-mediated immune responses, and cytokine production. The specific binding of this antibody to CD40 allows for accurate identification and characterization of CD40-expressing cells in research settings.

With its exceptional reactivity and validated performance in various experimental techniques, this antibody is essential for investigating immune system functions, vaccine development, and autoimmune disease mechanisms.Researchers in immunology, oncology, and infectious disease fields will find the Mouse CD40 Monoclonal Antibody (PE/Cyanine5.5 Conjugated, FGK4.5, FGK45) - AGEL0787 indispensable for advancing their understanding of immune responses and developing targeted interventions for immunological disorders and cancer therapy. Its ability to specifically target CD40 makes it a valuable tool in studying immune cell interactions and immune system modulation.

Product Title:PE/Cyanine5.5 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0787
Size:25µg, 100µg
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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