PE Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0142)

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SKU:
AGEL0142
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a
Clone:
FGK4.5/FGK45
Conjugation:
PE
Applications:
FC
Frequently bought together:

Description

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PE Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (PE-conjugated, FGK4.5, FGK45, AGEL0142) offered by AssayGenie is a valuable tool for researchers studying immune responses and cell signaling pathways. This antibody specifically targets the CD40 protein, a key regulator of immune cell activation and function.CD40 is a transmembrane protein found on various immune cells, including B cells, dendritic cells, and macrophages. It plays a crucial role in antigen presentation, B cell activation, and antibody production. The PE-conjugated format of this antibody allows for easy detection and quantification of CD40 expression in flow cytometry experiments.With its high specificity and sensitivity, the Mouse CD40 Monoclonal Antibody is an excellent choice for investigating the role of the CD40 pathway in immune responses, inflammation, and autoimmune diseases.

Researchers can use this antibody to explore the activation status of immune cells and monitor changes in CD40 expression under different experimental conditions.Whether you are studying immune cell interactions, vaccine development, or inflammatory disorders, the Mouse CD40 Monoclonal Antibody from AssayGenie provides reliable and reproducible results to advance your research efforts. Unlock the potential of CD40 signaling in immune regulation with this high-quality antibody.

Product Title:PE Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0142
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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