Biotin Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0141)

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SKU:
AGEL0141
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a
Clone:
FGK4.5/FGK45
Conjugation:
Biotin
Applications:
FC
Frequently bought together:

Description

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Biotin Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (Biotin Conjugated) FGK4.5 (FGK45) (AGEL0141) from AssayGenie is a powerful tool for research focused on CD40, a cell surface receptor critical in immune responses and inflammation regulation. This high-quality antibody, developed for use in mouse samples, is conjugated with biotin for versatile detection applications.CD40, a member of the tumor necrosis factor receptor superfamily, is a key regulator of immune system functions, including B cell activation and cytokine production. The FGK4.5 (FGK45) antibody specifically targets CD40, allowing for precise detection and analysis in various experimental settings. Its compatibility with biotin-based detection methods enhances flexibility in experimental design and facilitates multiplexing assays.

This antibody is invaluable for investigations into immune signaling pathways, antibody production, and immune cell interactions, making it ideal for studies in immunology, vaccine development, and autoimmune disease research. By elucidating the roles of CD40 in immune regulation, researchers can advance our understanding of immune responses and potentially uncover new therapeutic targets for diseases such as cancer, autoimmune disorders, and infectious diseases. Trust in AssayGenie for reliable tools to drive your research forward.

Product Title:Biotin Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0141
Size:25µg, 100µg
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Biotin Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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