GenieFluor 647 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0781)

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SKU:
AGEL0781
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
FGK4.5/FGK45
Conjugation:
AF 647
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (AF647 Conjugated FGK4.5) is a powerful tool for researchers studying CD40, a cell surface receptor essential for immune system function. This antibody, conjugated with AF647 for fluorescence detection, specifically targets CD40 in mouse samples and is validated for use in various immunological assays. It enables precise visualization and analysis of CD40 expression in different cell types, making it a valuable asset for investigating immune responses and potential therapeutic targets in diseases such as cancer, autoimmune disorders, and inflammatory conditions.

CD40 is a key player in mediating immune responses by facilitating interactions between immune cells, promoting cytokine production, and modulating cell proliferation. Understanding the role of CD40 in immune regulation is crucial for uncovering mechanisms underlying inflammatory diseases and developing immunotherapies. The Mouse CD40 Monoclonal Antibody provides researchers with a reliable tool to advance their studies in immunology, cancer research, and other fields where CD40 signaling is of interest.

Product Title:GenieFluor 647 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0781
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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