GenieFluor 488 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0780)

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SKU:
AGEL0780
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (AF488 Conjugated, FGK4.5, FGK45) is a powerful tool for researchers studying the CD40 cell surface molecule in mouse models. This monoclonal antibody, conjugated with AF488 for fluorescent detection, specifically targets and binds to the CD40 protein, facilitating its visualization and analysis in various experimental settings.CD40 is a crucial co-stimulatory molecule involved in immune responses, playing a fundamental role in the activation of B cells and antigen-presenting cells. By targeting CD40 with this high-quality monoclonal antibody, researchers can investigate its functions in immune system regulation, inflammation, and the development of immune responses in mouse models.

With its specificity and reliability, this CD40 monoclonal antibody is an essential tool for immunologists, cancer researchers, and those studying autoimmune conditions in preclinical studies. By understanding the mechanisms and effects of CD40 modulation, insights can be gained that may lead to the development of novel therapeutic approaches for a variety of diseases.

Product Title:GenieFluor 488 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0780
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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