The Mouse CD4 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, GK1.5) from Assay Genie (AGEL1252) is a highly specific tool designed for researchers studying CD4, a crucial cell surface protein involved in immune function. This antibody, derived from mouse cells, is optimized for flow cytometry applications, particularly in analyzing and sorting CD4-positive cell populations with precision and accuracy.CD4, also known as a coreceptor for the T cell receptor, is a key player in the immune response by facilitating T cell activation and differentiation. Targeting CD4-expressing cells is essential in understanding immune system dynamics and investigating diseases where T cell responses are dysregulated, such as autoimmune disorders, HIV, and various infections.
With its PerCP-Cyanine5.5 conjugation, this monoclonal antibody provides researchers with a reliable tool for visualizing and quantifying CD4 expression levels in various experimental settings. Whether investigating immune cell populations in cancer research, vaccination studies, or immunotherapy development, the Mouse CD4 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, GK1.5) offers a valuable resource for advancing our understanding of CD4 biology and its implications in immune-related research endeavors.
PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.