The Mouse CD4 Monoclonal Antibody (PERCP Conjugated, GK1.5) is a highly specialized tool for immunological research, particularly in the study of CD4-positive T cells. This unique antibody, conjugated with PERCP for flow cytometry applications, targets the CD4 marker with exceptional specificity and sensitivity. It enables precise detection and quantification of CD4 expression in various cell populations, thereby facilitating in-depth analysis of T cell subsets in both normal and pathological immune responses.CD4 is a crucial co-receptor on helper T cells that plays a central role in orchestrating immune reactions by interacting with MHC class II molecules on antigen-presenting cells. The GK1.5 monoclonal antibody, specifically designed for mouse CD4, provides researchers with a powerful tool to elucidate the function and behavior of CD4-positive T cells in different experimental settings, such as inflammation, infection, autoimmunity, and vaccination studies.
With its strong reactivity and reliable performance, the Mouse CD4 Monoclonal Antibody (PERCP Conjugated, GK1.5) from AssayGenie (Product Code: AGEL0358) offers a valuable resource for investigations focusing on T cell biology, immunotherapy, and immune-mediated diseases. This product empowers scientists to delve deeper into the intricacies of adaptive immunity, paving the way for novel insights and therapeutic advancements in the field of immunology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.